The epidermis was unremarkable [Figures 1,2]. In the mid-to-deep reticular dermis, there was a nodular proliferation of capillaries surrounded by an increased number of mature eccrine glands [Figures 3, 4] . These vessels were noted to be either dilated or collapsed due to the enlarged eccrine glands [Figures 5,6]. The lesion was well demarcated but not encapsulated.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Immunohistochemistry:
• Vascular immunohistochemistry:
The nodular proliferation of capillaries stained positively for CD31
[Figures 7,8].
Figure 7
Figure 8
• Eccrine ductal immunochemistry:
The secretory component of the eccrine ducts stained positively for
S100 [Figures 9, 10, 11].
Figure 9
Figure 10
Figure 11
The ductal components of the eccrine ducts stained positively for cytokeratin 1 (high molecular weight cytokeratin) [Figure 12].
Figure 12